MP80-07 SEX CORD-GONADAL STROMAL TUMORS OF THE TESTICLE ARE FAR MORE LETHAL THAN GERM CELL TESTICULAR NEOPLASMS
نویسندگان
چکیده
منابع مشابه
Expression of galectin-3 in gonads and gonadal sex cord stromal and germ cell tumors.
Galectin-3, a beta-galactoside-binding lectin, has been implicated in many human malignancies, but has seldom been studied in human gonads and gonadal tumors. The aim of our study was to investigate galectin-3 mRNA and protein expression in normal ovaries and testes as well as in a variety of 51 gonadal sex cord stromal and germ cell tumors, and two testicular seminomatous and non-seminomatous ...
متن کاملN-cadherin Expression in Testicular Germ Cell and Gonadal Stromal Tumors
Neural-cadherin is a member of the cadherin gene family encoding the N-cadherin protein that mediates cell adhesion. N-cadherin is a marker of Sertoli cells and is also expressed in germ cells of varying stages of maturation. The purpose of this study was to determine the presence and distribution of this protein by immunohistochemistry in 105 germ cell tumors of both single and mixed histologi...
متن کاملgenetics of testicular germ cell tumors
testicular germ cell tumor (tgct) is the most solid tumor in 20-40 years old man. tgct account for 95% of testicular tumors and represent a unique type of human cancer from several different perspectives. tgct arise by transformation of germ cells. the transformed germ cells exhibit ploripotentially to differentiate into embryonic. extra-embryonic, and somatic tissue types, and are highly sensi...
متن کاملOvary: Sex cord-stromal tumors
There appear to be several established clinical syndromes associated with several subtypes of sex cord-stromal tumours. 30% of patients with sex cord tumours with annular tubules have Peutz-Jeghers syndrome (PJS), an autosomal dominant disorder characterised by multiple gastrointestinal hamartomatous polyps, increased risk of various neoplasms, and melanocytic macules of the lips, buccal mucosa...
متن کاملBilateral testicular germ cell tumors.
Testicular cancer represents 1% to 1.5% of neoplasias in males and 5% of urologic tumors in general. The incidence of bilateral testicular tumors is 1-5%. Approximately one third of the cases are diagnosed as synchronous, while the other two thirds are diagnosed as metachronous tumors. Additionally, 5% of all patients diagnosed with testicular cancer may have contralateral intratubular germ cel...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of Urology
سال: 2017
ISSN: 0022-5347,1527-3792
DOI: 10.1016/j.juro.2017.02.2512